The subject may cross an ophthalmic subspecialty boundary, but the manuscript’s principal contribution must remain identifiable as ophthalmic science.
Clinical evaluation and disease management
Clinical research on anterior- and posterior-segment disease, including cornea, cataract, refractive care, glaucoma, retina and vitreous, uveitis, neuro-ophthalmology, pediatric ophthalmology, orbital and lacrimal disease, and ocular pathology or oncology.
Surgery, therapeutics and outcomes
Medical, surgical or rehabilitative interventions assessed with appropriate patient selection, comparators, outcome measures, follow-up and adverse-event reporting.
Imaging, diagnostics and measurement
Ophthalmic imaging, diagnostic-accuracy studies, biomarkers, functional testing and measurement methods that identify their reference standard, acquisition protocol and clinically relevant performance.
Basic, experimental and population research
Ocular biology, visual neuroscience, preclinical disease models, ophthalmic biomaterials, devices and engineering, together with epidemiology, prevention, rehabilitation, screening and access-to-care research.